Brain and Cognitive Function in Huntington’s Disease: A MEG Study

This type of memory can be affected in early stages of Huntington’s disease before motor symptoms occur.

Research featured image.

Dr Yifat Glikmann
Research Fellow and Clinical Neuropsychologist
Monash University


Why is spatial memory important in Huntington’s disease?

Spatial memory is the type of memory that helps us remember how to get to places in the environment (for example, going from home to work). This type of memory can be affected in early stages of Huntington’s disease before motor symptoms occur.

Tests of spatial memory are used in animals in the early stages of drug development, but not in later stages of drug trials in people with Huntington’s disease.

How am I investigating spatial memory?

I am using virtual reality technology to measure spatial memory in Huntington’s disease combined with Magneto-encephalography (MEG) to determine how, and wherein the brain, spatial memory is affected.

What will we learn from this research?

Our results will help improve the way new drugs for Huntington’s disease are assessed in terms of their effect on cognition (e.g., thinking, memory, learning).

For further information about the study including eligibility and participation requirements please contact Dr Yifat Glikmann-Johnston:

Contact person: Emily Mercieca
Email: med.memoryhd@monash.edu
Phone: 9903 4695
Address: Room 409A, Level 4, 18 Innovation Walk, Monash University, Clayton VIC 3800


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